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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GFM1
All Species:
25.15
Human Site:
S277
Identified Species:
42.56
UniProt:
Q96RP9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RP9
NP_079272.4
751
83471
S277
E
E
K
I
P
S
I
S
D
L
K
L
A
I
R
Chimpanzee
Pan troglodytes
XP_001154618
751
83449
S277
E
E
K
I
P
S
I
S
D
L
K
L
A
I
R
Rhesus Macaque
Macaca mulatta
XP_001094832
770
85971
S296
E
E
K
I
P
S
I
S
D
L
K
I
A
I
R
Dog
Lupus familis
XP_534320
771
85436
S297
E
E
K
I
P
S
V
S
D
L
K
C
A
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0D5
751
83531
S278
E
E
K
I
P
S
V
S
D
L
K
R
A
I
R
Rat
Rattus norvegicus
Q07803
751
83439
S278
E
E
K
I
P
S
V
S
D
L
K
L
A
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233639
738
82390
A265
E
E
K
I
P
T
V
A
D
I
K
L
A
I
R
Frog
Xenopus laevis
A5PKR8
748
83504
A275
E
E
K
I
P
T
V
A
D
L
K
P
A
I
R
Zebra Danio
Brachydanio rerio
Q08BB1
745
82731
L272
E
E
R
V
P
T
V
L
D
L
K
A
A
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM33
745
83491
D273
E
E
K
P
F
T
E
D
D
I
K
A
A
L
R
Honey Bee
Apis mellifera
XP_394825
744
84514
K277
N
E
I
Q
I
L
E
K
D
I
V
D
A
I
R
Nematode Worm
Caenorhab. elegans
Q9XV52
750
83636
Q275
N
D
Q
T
P
N
V
Q
Q
I
H
E
A
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C641
754
83160
S296
N
D
E
P
V
S
A
S
E
L
E
E
A
I
R
Baker's Yeast
Sacchar. cerevisiae
P25039
761
84555
Q305
E
E
K
E
P
T
T
Q
Q
I
K
D
A
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.6
88.9
N.A.
90.4
90.4
N.A.
N.A.
81.3
80.2
78
N.A.
65.1
61.9
55.2
N.A.
Protein Similarity:
100
100
96.4
93.9
N.A.
94.8
95.2
N.A.
N.A.
90.5
89.7
89.8
N.A.
78.8
77.2
71.3
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
93.3
N.A.
N.A.
73.3
73.3
53.3
N.A.
46.6
33.3
26.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
100
93.3
86.6
N.A.
66.6
40
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
53.7
53.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.2
70.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
15
0
0
0
15
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
8
79
0
0
15
0
0
0
% D
% Glu:
79
86
8
8
0
0
15
0
8
0
8
15
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
58
8
0
22
0
0
36
0
8
0
86
0
% I
% Lys:
0
0
72
0
0
0
0
8
0
0
79
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
8
0
65
0
29
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
15
79
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
8
8
0
0
0
15
15
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
100
% R
% Ser:
0
0
0
0
0
50
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
36
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
50
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _